Clonazepam’s effects last about 8 to 12 hours, therefore the clonazepam dosage for healthy adults is 2 to three times each day . It works quickly, usually within an hour, and reaches peak levels by about four hours. The clonazepam half-life is long at 30 to 40 hours. this suggests it can take several days to rid the body of it
Get an summary of CLONAZEPAM (tablet), including its generic name, formulation (i.e. pill, oral solution, injection, inhaled medicine) and why it’s used. The medication in Clonazepam are often sold under different names.
Refer to the “Also Known As” section to reference different products that include an equivalent medication as Clonazepam.
Drug Basics
Brand Name: Clonazepam
Generic Name: CLONAZEPAM
Drug Type: HUMAN prescription
Route: ORAL
Dosage Form: TABLET
Indications & Usage
Seizure Disorders
Clonazepam tablets USP are useful alone or as an adjunct within the treatment of the Lennox-Gastaut syndrome (petit mal variant), akinetic and myoclonic seizures. In patients with absence seizures (petit mal) who have did not answer succinimides, clonazepam tablets USP could also be useful.
In some studies, up to 30% of patients have shown a loss of anticonvulsant activity, often within 3 months of administration. In some cases, dosage adjustment may reestablish efficacy.
Panic Disorder
Clonazepam tablts USP are indicated for the treatment of anxiety disorder , with or without agoraphobia, as defined in DSM-IV. anxiety disorder is characterized by the occurrence of unexpected panic attacks and associated concern about having additional attacks, worry about the implications or consequences of the attacks, and/or a big change in behavior associated with the attacks.
The efficacy of clonazepam tablets USP was established in two 6 to 9 week trials in anxiety disorder patients whose diagnoses corresponded to the DSM-IIIR category of anxiety disorder (see CLINICAL PHARMACOLOGY, Clinical Trials).
Panic disorder (DSM-IV) is characterized by recurrent unexpected panic attacks, i.e., a discrete period of intense fear or discomfort during which four (or more) of the subsequent symptoms develop abruptly and reach a peak within 10 minutes: (1) palpitations, pounding heart or accelerated heart rate; (2) sweating; (3) trembling or shaking; (4) sensations of shortness of breath or smothering; (5) feeling of choking; (6) pain or discomfort; (7) nausea or abdominal distress; (8) feeling dizzy, unsteady, lightheaded or faint; (9) derealization (feelings of unreality) or depersonalization (being detached from oneself); (10) fear of losing control; (11) fear of dying; (12) paresthesias (numbness or tingling sensations); (13) chills or hot flushes.
The effectiveness of clonazepam tablets USP in long-term use, that is, for quite 9 weeks, has not been systematically studied in controlled clinical trials. The physician who elects to use clonazepam tablets USP for extended periods should periodically reevaluate the long-term usefulness of the drug for the individual patient (see DOSAGE AND ADMINISTRATION).
Contraindications
Clonazepam shouldn’t be utilized in patients with a history of sensitivity to benzodiazepines, nor in patients with clinical or biochemical evidence of serious disease . it’s going to be utilized in patients with open angle glaucoma who are receiving appropriate therapy but is contraindicated in acute narrow angle glaucoma.
- Drug Abuse & Dependence
- Controlled Substance Class
- Clonazepam may be a Schedule IV drug .
- Physical & Psychological Dependence
Withdrawal symptoms, similar in character to those noted with barbiturates and alcohol (e.g., convulsions, psychosis, hallucinations, behavioral disorder, tremor, abdominal and muscle cramps) have occurred following abrupt discontinuance of clonazepam. The more severe withdrawal symptoms have usually been limited to those patients who received excessive doses over an extended period of your time . Generally milder withdrawal symptoms (e.g., dysphoria and insomnia) are reported following abrupt discontinuance of benzodiazepines taken continuously at therapeutic levels for several months. Consequently, after extended therapy, abrupt discontinuation should generally be avoided and a gradual dosage tapering schedule followed (see DOSAGE AND ADMINISTRATION). Addiction-prone individuals (such as drug addicts or alcoholics) should be under careful surveillance when receiving clonazepam or other psychotropic agents due to the predisposition of such patients to habituation and dependence.
Following the short-term treatment of patients with anxiety disorder in Studies 1 and a couple of (see CLINICAL PHARMACOLOGY, Clinical Trials), patients were gradually withdrawn during a 7 week downward-titration (discontinuance) period. Overall, the discontinuance period was related to good tolerability and a really modest clinical deterioration, without evidence of a big rebound phenomenon. However, there aren’t sufficient data from adequate and well-controlled long-term clonazepam studies in patients with anxiety disorder to accurately estimate the risks of withdrawal symptoms and dependence which will be related to such use.
Medication Guide
Read this Medication Guide before you begin taking clonazepam tablets and every time you get a refill. There could also be new information. This information doesn’t take the place of lecture your healthcare provider about your medical condition or treatment.
Clonazepam tablets can cause serious side effects. Because stopping clonazepam tablets suddenly also can cause serious problems, don’t stop taking clonazepam tablets without lecture your healthcare provider first.
What is the foremost important information I should realize clonazepam tablets?
Do not stop taking clonazepam tablets without first lecture your healthcare provider.
Stopping clonazepam tablets suddenly can cause serious problems.
Clonazepam tablets can cause serious side effects, including:
- Clonazepam tablets can slow your thinking and motor skills
Do not drive, operate heavy machinery, or do other dangerous activities until you recognize how clonazepam tablets affect you.
Do not drink alcohol or take other drugs which will cause you to sleepy or dizzy while taking clonazepam tablets until you ask your healthcare provider. When crazy alcohol or drugs that cause sleepiness or dizziness, clonazepam tablets may make your sleepiness or dizziness worse.
- Like other antiepileptic drugs, clonazepam tablets may cause suicidal thoughts or actions during a very small number of individuals , about 1 in 500.
- thoughts about suicide or dying
- attempt to kill
- new or worse depression
- new or worse anxiety
- feeling agitated or restless
- panic attacks
- trouble sleeping (insomnia)
- new or worse irritability
- acting aggressive, being angry, or violent
- acting on dangerous impulses
- an extreme increase in activity and talking (mania)
- other unusual changes in behavior or mood
How am i able to await early symptoms of suicidal thoughts and actions?
Pay attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings.
Keep all follow-up visits together with your healthcare provider as scheduled.
Call your healthcare provider between visits as required , especially if you’re worried about symptoms.
Suicidal thoughts or actions are often caused by things aside from medicines. If you’ve got suicidal thoughts or actions, your healthcare provider may check for other causes.
Do not stop clonazepam tablets without first lecture a healthcare provider.
Stopping clonazepam tablets suddenly can cause serious problems. Stopping clonazepam tablets suddenly can cause seizures which will not stop (status epilepticus).
- Clonazepam tablets may harm your unborn or developing baby.
If you’re taking clonazepam tablets during pregnancy, your baby is in danger for serious birth defects. These defects can happen as early as within the first month of pregnancy, even before you recognize you’re pregnant. Birth defects may occur even in children born to women who aren’t taking any medicines and don’t produce other risk factors.
Children born to mothers receiving benzodiazepine medications (including clonazepam tablets) late in pregnancy could also be at some risk of experiencing breathing problems, feeding problems, hypothermia, and withdrawal symptoms.
Tell your healthcare provider directly if you become pregnant while taking clonazepam tablets. You and your healthcare provider should decide if you’ll take clonazepam tablets while you’re pregnant.
If you become pregnant while taking clonazepam tablets, ask your healthcare provider about registering with the North American anticonvulsant Pregnancy Registry. the aim of this registry is to gather information about the security of antiepileptic drugs during pregnancy.
Clonazepam can pass into breast milk. ask your healthcare provider about the simplest thanks to feed your baby if you’re taking clonazepam tablets. You and your healthcare provider should decide if you’ll take clonazepam tablets or breast feed. you ought to not do both.
- Clonazepam tablets can cause abuse and dependence.
Do not stop taking clonazepam tablets all of a sudden. Stopping clonazepam tablets suddenly can cause seizures that don’t stop, hearing or seeing things that aren’t there (hallucinations), shaking, and stomach and muscle cramps.
Talk to your doctor about slowly stopping clonazepam tablets to avoid getting sick with withdrawal symptoms.
Physical dependence isn’t an equivalent as white plague . Your healthcare provider can tell you more about the differences between physical dependence and white plague .
Clonazepam tablets are a federally drug (C-IV) because they will be abused or cause dependence. Keep clonazepam tablets during a safe place to stop misuse and abuse. Selling or making a gift of clonazepam tablets may harm others, and is against the law. Tell your doctor if you’ve got ever abused or been hooked in to alcohol, prescription medicines or street drugs.
What are clonazepam tablets?
Clonazepam tablets are a prescription drug used alone or with other medicines to treat:
certain sorts of seizure disorders (epilepsy) in adults and youngsters
panic disorder with or without worrying of open spaces (agoraphobia) in adults
It is not known if clonazepam tablets are safe or effective in treating anxiety disorder in children younger than 18 years old.
Who shouldn’t take clonazepam tablets?
Do not take clonazepam tablets if you:
- are allergic to benzodiazepines
- have significant disease
- have an eye fixed disease called acute narrow angle glaucoma
- Ask your healthcare provider if you’re unsure if you’ve got any of the issues listed above.
What should I tell my healthcare provider before taking clonazepam tablets?
Before you’re taking clonazepam tablets tell your healthcare provider if you:
- have liver or kidney problems
- have lung problems (respiratory disease)
- have or have had depression, mood problems, or suicidal thoughts or behavior
- have the other medical conditions
Tell your healthcare provider about all the medicines you’re taking , including prescription and non-prescription medicines, vitamins, and herbal supplements. Taking clonazepam tablets with certain other medicines can cause side effects or affect how well they work. don’t start or stop other medicines without lecture your healthcare provider.
How should I take clonazepam tablets?
Take clonazepam tablets exactly as your healthcare provider tells you.
Do not stop taking clonazepam tablets without first lecture your healthcare provider. Stopping clonazepam tablets suddenly can cause serious problems.
Clonazepam tablets should be crazy water and swallowed whole.
If you’re taking too many clonazepam tablets call your healthcare provider or local Poison center directly .
What should I avoid while taking clonazepam tablets?
Clonazepam tablets can slow your thinking and motor skills. don’t drive, operate heavy machinery, or do other dangerous activities until you recognize how clonazepam tablets affect you.
Do not drink alcohol or take other drugs which will cause you to sleepy or dizzy while taking clonazepam tablets until you ask your healthcare provider. When crazy alcohol or drugs that cause sleepiness or dizziness, clonazepam tablets may make your sleepiness or dizziness worse.
What are the possible side effects of clonazepam tablets?
See “What is that the most vital information I should realize clonazepam tablets?”
Clonazepam tablets also can make your seizures happen more often or make them worse. Call your healthcare provider directly if your seizures worsen while taking clonazepam tablets.
The most common side effects of clonazepam tablets include:
- Drowsiness
- Problems with walking and coordination
- Dizziness
- Depression
- Fatigue
- Problems with memory
These aren’t all the possible side effects of clonazepam tablets. For more information, ask your healthcare provider or pharmacist.
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