Robaxin may be a name of the generic medication methocarbamol. Methocarbamol may be a central systema nervosum depressant that’s wont to treat smooth muscle spasms. Robaxin features a relatively short half-life. In healthy individuals, nearly all methocarbamol metabolites are excreted within the urine within four hours of ingesting the drug.
Robaxin (Methocarbamol) Prescription Facts
Mothers who are pregnant should avoid taking Robaxin thanks to an increased likelihood of the infant being born with congenital birth defects. Methocarbamol is present within the milk of lactating mothers receiving treatment with the drug. it’s unknown whether this might be damaging to the event of nursing infants. Methocarbamol should be avoided when driving an automobile or operating heavy machinery thanks to the potential for impaired motor skills.
Robaxin (Methocarbamol) Regulations
Methocarbamol isn’t a secure treatment for several elderly patients thanks to the increased risk for serious side effects. Common side effects of Robaxin may include indigestion , flushing of the skin, poor coordination (ataxia), dizziness, blurred vision and drowsiness. Cases of rapid pulse (tachycardia) and slow pulse (bradycardia) are reported on rare occasions. These are serious conditions and will be reported to the prescribing doctor immediately. Other side effects that are indicative of a poor reaction to the drug include itching, jaundice (yellow skin and eyes), fainting, nausea, vomiting, difficulty urinating, mood swings and abdominal pain. Incidences of increased suicidal thoughts are uncommon but are more likely to occur in young patients taking high doses of methocarbamol.
Most Commonly Abused Drugs Containing Robaxin (Methocarbamol)
Robaxin is taken into account low-risk for developing a dependence on the drug. Abruptly stopping treatment can cause the increased likelihood of side effects. Methocarbamol features a tendency for addiction just like the benzodiazepine lorazepam, although the addictive qualities of methocarbamol are considerably weaker. Occurrences of addiction to methocarbamol alone is rare. Typical habits evolve in individuals with a history of addiction to other substances.
How Robaxin (Methocarbamol) Affects The Brain And Body
Robaxin features a high therapeutic index. this suggests that it tends to be effective and safe at a good range of doses. Daily doses of 500 mg to 750 mg are common for the treatment of persistent involuntary muscles spasms. Significantly higher doses could also be necessary for the treatment of lockjaw that’s related to tetanus. Severe side effects are more likely to occur at higher doses. the precise mechanism of action of methocarbamol is unknown. Robaxin doesn’t act directly on striatal muscle fibers but rather inhibits the functioning of the neurons that trigger the muscle twitching and pain. By depressing the activity of those neurons, symptoms are often reduced.
Half-Life Of Robaxin (Methocarbamol)
The plasma elimination half-life of methocarbamol ranges between one and two hours before being excreted within the urine. Nearly all of methocarbamol’s metabolites are excreted within the urine. Only a miniscule amount of methocarbamol itself is eliminated within the urine. The protein binding of methocarbamol ranges from 46 percent to 50 percent in healthy individuals.
Factors That Influence How Long Robaxin (Methocarbamol) Stays In Your System
The patient’s age, the health of their kidneys and therefore the health of their liver all influence the metabolism of Robaxin within the body. Elderly patients of a mean age of 69 take slightly longer to eliminate methocarbamol within the urine. differently to mention this is often that methocarbamol features a shorter half-life in elderly patients. The elderly population with a mean age of 69 takes roughly 1.5 hours to eliminate Robaxin, while patients with a mean age of 53 combat average 1.1 hours to excrete the drug.
The older patients also display a decreased fraction of bound methocarbamol within the blood, meaning that younger patients utilize the drug more effectively. Patients on hemodialysis thanks to poorly functioning kidneys absorb and utilize methocarbamol less efficiently at a clearance rate of only 40 percent compared to 46 percent to 50 percent in healthy patients. Individuals with cirrhosis of the liver thanks to alcohol misuse have a similarly poor rate of effectiveness, with only 40 percent to 45 percent of methocarbamol bonding to plasma proteins.
How Long Does Robaxin (Methocarbamol) Stay In Your Urine, Hair And Blood?
Testable levels of methocarbamol metabolites could also be present within the urine beginning one to 2 hours following ingestion. Methocarbamol can remain within the urine for up to four hours following the time of ingestion. These ranges can vary counting on the age and health of the patient. for many individuals, only two percent of absorbed methocarbamol will remain within the blood at 24 hours following the ultimate dose of the drug. As is that the case with most substances, Robaxin could also be tested for via a hair sample within 90 days of the last treatment.